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HRID862657

反应详情

EQUATION

反应方程式

HRID 862657 的结构方程式

REACTANTS

反应物

2
结构：COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1
HCID87949

p-Anisyldithiophosphonic anhydride

C14H14O2P2S4

结构：CCOC(=O)c1c(-c2ccc(OC)c(OC)c2)c2cc(OC)c(OC)cc2[nH]c1=O
HCID22097611

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(=O)c1c(S)nc2cc(OC)c(OC)cc2c1-c1ccc(OC)c(OC)c1
HCID178470133

未命名化合物

收率 70.8%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：Cc1ccccc1
溶剂HCID1140

Toluene

C7H8

PROCEDURE

实验过程

A mixture of ethyl 6,7-dimethoxy-4-(3,4-dimethoxyphenyl)-2(1H)-quinolone-3-carboxylate (6.8 g), Lawesson's reagent (8.0 g) and toluene (250 ml) was stirred under reflux for 18 hours. After cooling, the precipitated crystals were collected by filtration to give ethyl 6,7-dimethoxy-4-(3,4-dimethoxyphenyl)-2-mercaptoquinoline-3-carboxylate (5.0 g, 70%) which was then recrystallized from acetone. mp. 265°-266° C.

WORKUP

后处理

  1. temperatureunder reflux for 18 hours
  2. temperatureAfter cooling
  3. filtrationthe precipitated crystals were collected by filtration