O-Methylhydroxylamine hydrochloride → 2-Bromophenylglyoxylic Acid Methyl Ester-O-methyloxime

HRID 862662Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 862662
Cl.[CH3:2][O:3][NH2:4].[Br:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[C:12](=O)[C:13]([O:15][CH3:16])=[O:14]>CO>[CH3:2][O:3][N:4]=[C:12]([C:7]1[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=1[Br:5])[C:13]([O:15][CH3:16])=[O:14]

Komponenten

4

Edukt 2

HCID 521874O-Methylhydroxylamine hydrochlorideHCID 10890094Methyl 2-(2-bromophenyl)-2-oxoacetate

Produkt 1

HCID 537288432-Bromophenylglyoxylic Acid Methyl Ester-O-methyloxime

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

5.2 g (62 mmol) of O-methylhydroxylamine hydrochloride is added to a solution of 10 g (41 mmol) of methyl 2-bromophenylglyoxylate in 30 ml of methanol, and the mixture is refluxed for 2 hours. The mixture is evaporated down, and the residue is taken up in ethyl acetate and washed with water. After drying and evaporating down, there remains 6.9 g (62%) of compound E.

Aufarbeitung

  1. temperaturethe mixture is refluxed for 2 hours
  2. customThe mixture is evaporated down
  3. washwashed with water
  4. customAfter drying
  5. customevaporating down

Quellen und Nachweise

ORD-Eintrag
ord-e70e133d41f641d58f0a437544cd0162
Quelldatensatz
uspto-grants-1998_02
Patentnummer
US05719171

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