反应详情

To a solution (10 ml) of 2-acetamido-1,3-diacetoxy-2-(4-octylsulfinylbenzyl)propane (330 mg) in chloroform was added m-chloroperbenzoic acid (244 mg) under ice-cooling. The mixture was stirred for 2.5 hours and then at room temperature for 1.5 hours. Calcium hydroxide (0.1 g) was added to the reaction mixture and the mixture was stirred at room temperature for 45 minutes. The insoluble matters were filtered off and the filtrate was concentrated under reduced pressure. The residue was recrystallized from hexane-ethyl acetate to give 162 mg of the subject compound.

1. temperaturecooling
2. waitat room temperature for 1.5 hours
3. stirringthe mixture was stirred at room temperature for 45 minutes
4. filtrationThe insoluble matters were filtered off
5. concentrationthe filtrate was concentrated under reduced pressure
6. customThe residue was recrystallized from hexane-ethyl acetate