Phthalic Anhydride → HCID 19698913, compound

HRID 862888Notes

Reaction equation

HRID 862888 reaction equation
[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH:8](NC)[CH3:9].[C:12]1(=[O:22])[O:17][C:15](=O)[C:14]2=[CH:18][CH:19]=[CH:20][CH:21]=[C:13]12.[CH2:23]([N:25](CC)CC)C>C1(C)C=CC=CC=1>[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH:8]([CH3:9])[CH2:23][N:25]1[C:12](=[O:22])[C:13]2=[CH:21][CH:20]=[CH:19][CH:18]=[C:14]2[C:15]1=[O:17]

Participants

5

Reactant 3

HCID 6811Phthalic AnhydrideHCID 8471TriethylamineHCID 19698939HCID 19698939, compound

Product 1

HCID 19698913HCID 19698913, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

8-Bromo-2-methylaminooctane is treated with phthalic anhydride in toluene in the presence of triethylamine under reflux. The solvent is removed in vacuo. The residue, when triturated with water, acidified with hydrochloric acid and crystallized from alcohol will yield N-(8-bromo-2-methyloctyl)phthalimide.

Workup

  1. temperatureunder reflux
  2. customThe solvent is removed in vacuo
  3. customThe residue, when triturated with water
  4. customcrystallized from alcohol

Sources & evidence

ORD record
ord-73fa4912af614edda43f49e95951dd79
Source dataset
uspto-grants-1998_02
Patent number
US05719271

Reaction notes

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