3,4-dihydro-2H-pyran → 2-[(7-Bromoheptyl)oxy]tetrahydro-2H-pyran
Reaction equation
BrCCCCCCCO.[O:10]1[CH2:15][CH2:14][CH2:13][CH2:12][CH:11]1[O:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][Br:24].O1C=CCCC1>>[O:10]1[CH2:15][CH2:14][CH2:13][CH2:12][CH:11]1[O:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][Br:24]Participants
3
Procedure
1-O-(Tetrahydropyran-2-yl)-7-bromoheptanol 7-Bromoheptanol will be treated with dihydropyrane in the presence of acid to give 1-O-(tetrahydropyran-2-yl)-7-bromoheptanol.
Sources & evidence
- ORD record
- ord-d0d94c1777f74bceb7876d777eb52f8a
- Source dataset
- uspto-grants-1998_02
- Patent number
- US05719271
Reaction notes
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