Hydrazinecarboxaldehyde → HCID 67640970, compound

HRID 863080Notes

Reaction equation

HRID 863080 reaction equation
[CH2:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][C:2]1=O.[CH:12]([NH:14][NH2:15])=[O:13]>C(O)C.Cl>[CH:12]([NH:14][N:15]=[C:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][CH2:2]1)=[O:13]

Participants

5

Reactant 2

HCID 12229HydrazinecarboxaldehydeHCID 682662-Tetralone

Product 1

HCID 67640970HCID 67640970, compoundYield 36.3%

Reagents, catalysts & solvents 2

HCID 313Hydrochloric AcidCatalystHCID 702EthanolSolvent

Conditions

Temperature
70 °C

Procedure

A mixture of 1,2,3,4-tetrahydronaphthalen-2-one (3.5 g, 24.0 mmol) and formic hydrazide (1.56 g, 26.0 mmol) in 25 mL of ethanol and 1 drop of concentrated hydrochloric acid was heated at 70° C. for 1 hour. The mixture was cooled to room temperature giving a crystalline material. The material was isolated by filtration and washed with ethanol. Drying gave 2-formylhydrazono-1,2,3,4-tetrahydronaphthalene (3.5 g, 8.7 mmol).

Workup

  1. temperatureThe mixture was cooled to room temperature
  2. customgiving a crystalline material
  3. customThe material was isolated by filtration
  4. washwashed with ethanol
  5. customDrying

Sources & evidence

ORD record
ord-3dde37189e2c47afbc45affdccf468b6
Source dataset
uspto-grants-1998_02
Patent number
US05719280

Reaction notes

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