Trifluoroacetic acid → HCID 54037813, compound

HRID 863092Notes

Reaction equation

[CH2:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][CH:2]1[N:11]1[CH:15]=[CH:14][N:13]([CH2:16][C:17]([O:19]C(C)(C)C)=[O:18])[C:12]1=[S:24].FC(F)(F)C(O)=O>>[CH2:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][CH:2]1[N:11]1[CH:15]=[CH:14][N:13]([CH2:16][C:17]([OH:19])=[O:18])[C:12]1=[S:24]

Participants

Reactant 2

HCID 6422Trifluoroacetic acid

HCID 54559494HCID 54559494, compound

Product 1

HCID 54037813HCID 54037813, compound

Procedure

substituting tert-butyl 3-(1,2,3,4-tetrahydronaphthalen-2-yl)-2-thioxo-2,3-dihydro-1H-imidazol-1-ylacetate and trifluoroacetic acid gave 3-(1,2,3,4-tetrahydronaphthalen-2-yl)-2-thioxo-2,3-dihydro-1H-imidazol-1-yl-acetic acid, m.p. 228°-230° C.;

Sources & evidence

ORD record: ord-f1275ffc99ce4b4ebcf1e0effd3902c9
Source dataset: uspto-grants-1998_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05719280

Reaction notes

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