反应详情

1.87 g of N-benzyloxycarbonyl-1,2,3,4-tetrahydroquinoline-3(R,S)-carboxylic acid and 5 ml of N,N-dimethylformamide dimethyl acetal are heated at 80° C. in 20 ml of toluene for 4 h. The reaction mixture is concentrated and the residue is purified by means of FC (50 g of silica gel, mobile phase D): Rf (D)=0.29; MS: (M)+ =325.

1. concentrationThe reaction mixture is concentrated
2. customthe residue is purified by means of FC (50 g of silica gel, mobile phase D)