HCID 19697711, compound → HCID 19697826, compound

Participants

Reaction Steps

868 mg of 1-benzyl-3(R,S)-acetyl-1,2,3,4-tetrahydroquinoline are hydrogenated to saturation in 100 ml of tetrahydrofuran in the presence of 100 mg of palladium-on-charcoal (10% of Pd) under normal pressure at room temperature. The reaction mixture is filtered and the concentrated filtrate is purified by means of FC over 50 g of silica gel (mobile phase B). This gives the title compound: Rf (A)=0.29; Rf (D)=0.08.

Provenance & Evidence