HuagongsheHuagongshe Chemistry Print Report · For research reference only
Nitrogen → HCID 15228156, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Nitrogen | HCID 947 | — |
| Reactant | Ethyl Acetoacetate | HCID 8868 | — |
| Reactant | (2Z)-3-Amino-2-butenenitrile | HCID 5325263 | — |
| Reactant | HCID 19696475 | HCID 19696475 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 15228156 | HCID 15228156 | — |
Reaction Steps
2 g (8.54 mmol) of 3-phenyl-1,8-naphthyridine-5-carboxaldehyde, 0.7 g (8.54 mmol) of 3-aminocrotononitrile and 1.08 ml of ethyl acetoacetate (8.54 mmol) are boiled in 16 ml of ethanol in an N2 atmosphere for 16 hours. Chromatography over silica gel and elution with ethyl acetate gives 0.38 g (10.8% of theory) of the title compound of melting point 265° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05721248 |
| Source dataset | uspto-grants-1998_02 |
| ORD ID | ord-f0cbba4b0d3d44eb8cc6edb744860d6a |
| Source note | uspto-grants-1998_02 |