Hydrochloric Acid → HCID 86752147, compound

HRID 863526Notes

Reaction equation

HRID 863526 reaction equation
[N:1]#[N:2].[CH3:3][CH:4]1[C:12]2[C:7](=[C:8]([N+:18]([O-:20])=[O:19])[C:9]([NH:14]C(=O)C)=[C:10]([Br:13])[CH:11]=2)[CH2:6][CH:5]1[NH:21]C(=O)C.[ClH:25]>C(O)(=O)C>[N:1]#[N:2].[ClH:25].[CH3:3][CH:4]1[C:12]2[C:7](=[C:8]([N+:18]([O-:20])=[O:19])[C:9]([NH2:14])=[C:10]([Br:13])[CH:11]=2)[CH2:6][CH:5]1[NH2:21]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 86752145HCID 86752145, compound

Product 1

HCID 86752147HCID 86752147, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Conditions

Temperature
100 °C

Procedure

A mixture of N2 -methyl-2,5-diacetamido-6-bromo-4-nitroindane (22.5 g, 61 mmol) in 3N HCl (150 mL) and acetic acid (50 mL) was heated at 100° C. for 24 h. The mixture was cooled in an ice bath and the orange precipitate was collected by filtration and dried (17.2 g).

Workup

  1. temperatureThe mixture was cooled in an ice bath
  2. filtrationthe orange precipitate was collected by filtration
  3. customdried (17.2 g)

Sources & evidence

ORD record
ord-2d83098898034772877b76ddee85339f
Source dataset
uspto-grants-1998_02
Patent number
US05721234

Reaction notes

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