Nitric Acid → HCID 19696225, compound

HRID 863530Notes

Reaction equation

HRID 863530 reaction equation
[N:1]1([CH:6]2[CH2:20][C:9]3[C:10]4[NH:11][C:12](=[O:19])[C:13](=[O:18])[NH:14][C:15]=4[CH:16]=[CH:17][C:8]=3[CH2:7]2)[CH2:5][CH2:4][CH2:3][CH2:2]1.[N+:21]([O-])([OH:23])=[O:22]>FC(F)(F)C(O)=O>[N+:21]([C:17]1[C:8]2[CH2:7][CH:6]([N:1]3[CH2:5][CH2:4][CH2:3][CH2:2]3)[CH2:20][C:9]=2[C:10]2[NH:11][C:12](=[O:19])[C:13](=[O:18])[NH:14][C:15]=2[CH:16]=1)([O-:23])=[O:22]

Participants

4

Reactant 2

HCID 944Nitric AcidHCID 19696259HCID 19696259, compound

Product 1

HCID 19696225HCID 19696225, compound

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Procedure

Nitration of 8-pyrrolidin-1-yl-4,7,8,9-tetrahydro-1H-cyclopenta[f]quinoxaline-2,3-dione as described before with fuming nitric acid in trifluoroacetic acid gave the product as a yellow solid (0.1 g). C15H16N4 O4.HCL. MS M+1 (317). HPLC 99%.

Sources & evidence

ORD record
ord-5b23b549af3844909f553ef749c31e07
Source dataset
uspto-grants-1998_02
Patent number
US05721234

Reaction notes

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