HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanesulfonic Acid → HCID 86752152, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanesulfonic Acid | HCID 6395 | — |
| Reactant | HCID 53856125 | HCID 53856125 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 86752152 | HCID 86752152 | 90.6% |
Reaction Steps
To a solution of (2S,3S)-N-(2-methoxy-5-methylsulfonylphenyl)methyl-2-diphenylmethyl-1-azabicyclo[2.2.2]octan-3-amine (400 mg, 0.82 mmol) in acetone (10 mL) was added methanesulfonic acid (0.41 mmol, 39.2 mg). The precipitated white solid was filtered off to give the title compound (218 mg, 30.3%, 1st crop).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05721255 |
| Source dataset | uspto-grants-1998_02 |
| ORD ID | ord-dc1de828b900414b9045f77505d1865d |
| Source note | uspto-grants-1998_02 |