Benzene → 3-Methyl-indan-1-one

HRID 863613Notes

Reaction equation

HRID 863613 reaction equation
[Cl-].[Al+3].[Cl-].[Cl-].[C:5](O)(=[O:9])/[CH:6]=[CH:7]/[CH3:8].[CH:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>>[CH3:8][CH:7]1[C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[C:5](=[O:9])[CH2:6]1

Participants

4

Reactant 3

HCID 241BenzeneHCID 637090Crotonic AcidHCID 6451240Aluminum(III) Chloride

Product 1

HCID 2595603-Methyl-indan-1-one

Procedure

To 31.8 g of aluminum chloride, 6.8 g of crotonic acid and 50.0 ml of benzene were added and the mixture was reacted under reflux for 5 hours. After filtering the reaction solution, benzene was removed from the filtrate by distillation and the residue was distilled in a vacuum (120°-123° C./12 mmHg) to obtain 9.7 g of 3-methyl-1-indanone.

Workup

  1. customthe mixture was reacted
  2. temperatureunder reflux for 5 hours
  3. filtrationAfter filtering the reaction solution, benzene
  4. customwas removed from the filtrate by distillation
  5. distillationthe residue was distilled in a vacuum (120°-123° C./12 mmHg)

Sources & evidence

ORD record
ord-5d7cbad7a7464c4c8670e07c62b9b4ed
Source dataset
uspto-grants-1998_02
Patent number
US05721288

Reaction notes

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