Sodium Hydroxide → HCID 54512127, compound

Participants

Reaction Steps

A suspension of 8.0 g. (0.025 mole) of ethyl 5-(ρ-chlorobenzoyl)-1-methylpyrrole-2-propionate in 15 ml. ethanol and 30 ml. 1N sodium hydroxide is refluxed for one hour. The ethanol is then evaporated, and the remaining solution is poured into dilute hydrochloric acid. The remaining solution is poured into dilute hydrochloric acid. The resulting white precipitate is filtered off and purified by recrystallization from isopropyl alcohol, 5-(ρ-chlorobenzoyl)-1-methylpyrrole-2-propionic acid, M.P. 188°-191° C.

Provenance & Evidence