Dimethylformamide → HCID 19696319, compound

Participants

Reaction Steps

A solution of 400 mg of 3-[8-cyano-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methyl-3-indolyl)furan-2,5-dione in 12 ml of dimethylformamide and 12 ml of 33% aqueous ammonia was heated to 140° C. for 3 hours. The mixture was cooled and the resulting solid was filtered off and dried to give 275 mg of 3-[8-cyano-6,7,8,9-tetrahydropyrido-[1,2-a]indol-10-yl]-4-(1-methyl-3-indolyl)-1H-pyrrole-2,5-dione of melting point 312°-313° C.

Provenance & Evidence