Formic Acid → Methyl 8-bromo-1-formyl-1,2,3,4-tetrahydro-1-benzoazocine-5-carboxylate

HRID 86372Notes

Reaction equation

HRID 86372 reaction equation
[Br:11][c:12]1[cH:13][cH:14][c:15]2[c:16]([cH:27]1)[CH:17]=[C:18]([C:23](=[O:24])[O:25][CH3:26])[CH2:19][CH2:20][CH2:21][NH:22]2.[CH2:28]1[O:29][CH2:30][CH2:31][CH2:32]1.[CH3:4][C:5]([O:6][C:7](=[O:8])[CH3:9])=[O:10].[CH:1](=[O:2])[OH:3]>>[CH:1](=[O:2])[N:22]1[c:15]2[cH:14][cH:13][c:12]([Br:11])[cH:27][c:16]2[CH:17]=[C:18]([C:23](=[O:24])[O:25][CH3:26])[CH2:19][CH2:20][CH2:21]1

Participants

5

Reactant 4

HCID 284Formic AcidHCID 7918Acetic AnhydrideHCID 8028TetrahydrofuranHCID 68650133Methyl 8-bromo-1,2,3,4-tetrahydro-1-benzazocine-5-carboxylate

Product 1

HCID 86595586Methyl 8-bromo-1-formyl-1,2,3,4-tetrahydro-1-benzoazocine-5-carboxylate

Sources & evidence

ORD record
ord-4db927c115c5436c8fe629c5d50a89db
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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