HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → alpha-(5-Aminopentyl)-alpha-(cyclohexylthio)-3,4-dimethoxy benzeneacetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | a-(Cyclohexylthio)-alpha-(3,4-dimethoxyphenyl)-1,3-dioxo-2H-isoindole-2-heptanenitrile | HCID 10505769 | — |
| Product | alpha-(5-Aminopentyl)-alpha-(cyclohexylthio)-3,4-dimethoxy benzeneacetonitrile | HCID 10667266 | 88.8% |
Reaction Steps
The procedure of Example 25 is repeated using 2.0 g of α-(cyclohexylthio)-α-(3,4-dimethoxyphenyl)-1,3-dioxo-2H-isoindole-2-heptanenitrile and 3.0 mL of hydrazine hydrate. This affords 1.32 g of the desired product as a light yellow oil. Calcd for C21H32N2SO2 0.7M H2O: C=64.81, H=8.81, N=7.20, S=8.24 Found C=65.04, H=8.49, N=6.98, S=8.20
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05561141 |
| Source dataset | uspto-grants-1996_10 |
| ORD ID | ord-cf29ca37abc24b00ba2e734ff9988dd9 |
| Source note | uspto-grants-1996_10 |