HRID863903

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID24654

Hydrazine hydrate (1:1)

H6N2O

结构：COc1ccc(C(C#N)(CCCCCN2C(=O)c3ccccc3C2=O)SC2CCCCC2)cc1OC

HCID10505769

未命名化合物

PRODUCTS

生成物

结构：COc1ccc(C(C#N)(CCCCCN)SC2CCCCC2)cc1OC

HCID10667266

未命名化合物

收率 88.8%

PROCEDURE

实验过程

The procedure of Example 25 is repeated using 2.0 g of α-(cyclohexylthio)-α-(3,4-dimethoxyphenyl)-1,3-dioxo-2H-isoindole-2-heptanenitrile and 3.0 mL of hydrazine hydrate. This affords 1.32 g of the desired product as a light yellow oil. Calcd for C21H32N2SO2 0.7M H2O: C=64.81, H=8.81, N=7.20, S=8.24 Found C=65.04, H=8.49, N=6.98, S=8.20