HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzylamine → 2,3-Dihydro-5-methoxy-6-(phenylmethoxy)-2-(phenylmethyl)-1H-isoindole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzylamine | HCID 7504 | — |
| Reactant | Bis(chloromethyl)-4-methoxy-5-(phenylmethoxy)benzene | HCID 10591097 | — |
| Product | 2,3-Dihydro-5-methoxy-6-(phenylmethoxy)-2-(phenylmethyl)-1H-isoindole | HCID 10736303 | — |
Reaction Steps
The procedure of Example 26 is repeated using 1.0 g of bis(chloromethyl)-4-methoxy-5-(phenylmethoxy)benzene and 0.6 mL of benzyl amine. This affords 0.74 g of the desired product as a beige solid. mp 94°-96° C. MS(FAB): m/z 346 (M+H). Calcd for C23H23NO2 0.05M CH2Cl2 : C=79.16, H=6.66, N=4.01 Found C=78.96, H=6.76, N=3.87
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05561141 |
| Source dataset | uspto-grants-1996_10 |
| ORD ID | ord-52618f2b9f4a4611bab29f346a274cad |
| Source note | uspto-grants-1996_10 |