HCID 86749903, compound → HCID 145828514, compound

HRID 864320Notes

Reaction equation

HRID 864320 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4](/[C:8](=[N:14]/[O:15]CC(OC(C)(C)C)=O)/[C:9]([O:11][CH2:12]C)=[O:10])[CH:5]=[CH:6][CH:7]=1.[N+](C1C=C(/C(=N\O)/C(OC)=O)C=CC=1)([O-])=O>CO.[Pt](=O)=O>[NH2:1][C:2]1[CH:3]=[C:4](/[C:8](=[N:14]\[OH:15])/[C:9]([O:11][CH3:12])=[O:10])[CH:5]=[CH:6][CH:7]=1

Participants

5

Reactant 2

HCID 86749903HCID 86749903, compoundHCID 145828517HCID 145828517, compound

Product 1

HCID 145828514HCID 145828514, compound

Reagents, catalysts & solvents 2

HCID 345198Adams' catalystCatalystHCID 887MethanolSolvent

Procedure

Methyl (E)-3-amino-alpha-hydroxyiminophenylacetate can be obtained in the following manner: the reaction is carried out as in Example 9 for the preparation of ethyl (Z)-3-amino-alpha-tert-butoxycarbonylmethoxyimino-phenylacetate, but starting from 3.4 g of methyl (E)-3-nitro-alpha-hydroxyiminophenylacetate and 0.034 g of platinum dioxide in 20 cm3 of methanol. After treatment, 2.9 g of methyl (E)-3-amino-alpha-hydroxyiminophenylacetate are obtained in the form of a solid which is used as such in the subsequent syntheses.

Sources & evidence

ORD record
ord-6092071ac0874e249955b547a83ac3bd
Source dataset
uspto-grants-1996_10
Patent number
US05563136

Reaction notes

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