Ammonia → HCID 19418698, compound

Participants

Reaction Conditions

Reaction Steps

N-{(3-Nitrophenyl)methyl}acetohydroxamic acid can be obtained in the following manner: 22 cm3 of an 17N aqueous solution of ammonia are added at a temperature near to 25° C. to a solution of 3.55 g of N-acetoxy-N-{(3-nitrophenyl)methyl}acetamide in 120 cm3 of methanol. The reaction mixture is stirred for two hours at a temperature near to 25° C., and then concentrated under reduced pressure. The residue is dissolved in 100 cm3 of a saturated aqueous solution of sodium chloride, dried over magnesium sulphate and concentrated under reduced pressure. 2.46 g of N-{(3-nitrophenyl)methyl}acetohydroxamic acid melting at 80° C. are thus obtained.

Provenance & Evidence