HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-[5-Chloro-4-(1-methylethyl)amino-3-pyridazinyl]piperazine → 1-[4-(1-Methylethyl)amino-3-pyridazinyl]piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-[5-Chloro-4-(1-methylethyl)amino-3-pyridazinyl]piperazine | HCID 21477673 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | 1-[4-(1-Methylethyl)amino-3-pyridazinyl]piperazine | HCID 21477613 | — |
Reaction Steps
Following the general procedure of PREPARATION 28 and making non-critical variations but starting with 1-[5-chloro-4-(1-methylethyl)amino-3-pyridazinyl]piperazine (PREPARATION 32, 1.7 g) and triethylamine (0.81 g), the title compound is obtained, NMR (CDCl3) 1.28, 2.06, 3.05, 3.11, 3.59, 4.75, 6.39, and 8.49δ; CMR (CDCl3) 22.2, 43.2, 46.2, 50.6, 103.7, 138.7, 148.4 and 154.5δ.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05563142 |
| Source dataset | uspto-grants-1996_10 |
| ORD ID | ord-864356f0d6df4e9796f11f096b6182be |
| Source note | uspto-grants-1996_10 |