Phenyl-2-aminoethyl sulfide → N-Cyano-N'-(2-phenylthioethyl)-N"-3-pyridylguanidine

Participants

Reaction Steps

S-Methyl N-cyano-N'-3-pyridylisothiourea (1.92 g) was dissolved in pyridine (10 ml), and 2-phenylthioethylamine (3.06 g) was added. The mixture was kept at room temperature for 4 days, when it was evaporated in vacuo. The residue was triturated with ether (40 ml), and the resulting suspension was filtered and washed with ether.

Provenance & Evidence