Ammonia → HCID 86749908, compound

Participants

Reaction Steps

The suspension of 1.50 g of the compound (1) obtained in Example 1 in 50 ml of methanol saturated with ammonia was allowed to stand at 4° C. for 24 hours. The reaction solution was concentrated under reduced pressure. To the resulting residue water was added, and the precipitated product was filtered and washed with water, and ether successively. The resulting crude product was recrystallized with 2-propanol to obtain 600 mg (yield: 55.9%) of the title compound.

Provenance & Evidence