HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2R, 3R, 4S, 4aS, 10aR)-2-azidomethyl-8-chloro-3, 4-diacetoxy-10-(2-diethylaminoethyl)-2, 3, 4, 4a, 10, 10a-hexahydropyrano [3, 2-b] [1, 4] benzothiazine → HCID 86749917, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2R, 3R, 4S, 4aS, 10aR)-2-azidomethyl-8-chloro-3, 4-diacetoxy-10-(2-diethylaminoethyl)-2, 3, 4, 4a, 10, 10a-hexahydropyrano [3, 2-b] [1, 4] benzothiazine | HCID 86749915 | — |
| Solvent | Ammonia | HCID 222 | — |
| Product | HCID 86749917 | HCID 86749917 | — |
Reaction Steps
The compound (37) 10.1 g obtained in Example 36 was dissolved in 250 ml of ammonia-saturated methanol, and the solution was stirred for 6 hours at room temperature. The solvent was removed under reduced pressure to obtain the title compound quantitatively.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05563137 |
| Source dataset | uspto-grants-1996_10 |
| ORD ID | ord-26285adfd1794159b739c47b28d71795 |
| Source note | uspto-grants-1996_10 |