HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methylmorpholine → HCID 140376888, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methylmorpholine | HCID 7972 | — |
| Reactant | 4-[(Benzyloxycarbonyl)-methyl]-4-hydroxy-piperidine-hydrochloride | HCID 19419592 | — |
| Reactant | HCID 140376887 | HCID 140376887 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 140376888 | HCID 140376888 | — |
Reaction Steps
Prepared by reacting 2-[4-[N-(benzyloxycarbonyl)-amidino]-phenyl]-5-carboxy-pyrimidine with 1.2 equivalents of N,N-carbonyl-diimidazole in dimethylformamide at 5° C. followed by the addition of 1.2 equivalents of 4-[(benzyloxycarbonyl)-methyl]-4-hydroxy-piperidine-hydrochloride and 1.2 equivalents of N-methylmorpholine at ambient temperature.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05563268 |
| Source dataset | uspto-grants-1996_10 |
| ORD ID | ord-77dea8455d5f412599cce16b9445bfa6 |
| Source note | uspto-grants-1996_10 |