Phthalic Anhydride → HCID 23373457, compound

HRID 864679Notes

Reaction equation

HRID 864679 reaction equation
[C:1]1(=[O:11])[O:6][C:4](=[O:5])[C:3]2=[CH:7][CH:8]=[CH:9][CH:10]=[C:2]12.C([O:14][C:15](=[O:29])[CH:16]([CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)C.[Cl-].[Al+3].[Cl-].[Cl-]>CN(C=O)C>[CH2:23]([CH:16]([C:17]1[CH:18]=[CH:19][C:20]([C:4](=[O:5])[C:3]2[CH:7]=[CH:8][CH:9]=[CH:10][C:2]=2[C:1]([OH:6])=[O:11])=[CH:21][CH:22]=1)[C:15]([OH:29])=[O:14])[CH2:24][CH2:25][CH2:26][CH2:27][CH3:28]

Participants

5

Reactant 3

HCID 6811Phthalic AnhydrideHCID 6451240Aluminum(III) ChlorideHCID 12609602HCID 12609602, compound

Product 1

HCID 23373457HCID 23373457, compoundYield 18%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

The ethyl ester of the titled product was prepared in 18% yield by reacting phthalic anhydride and α-hexylbenzeneacetic acid ethyl ester in the presence of aluminum chloride in DMF according to the general procedure of Example 55. The title product was then prepared according to the procedure of Example 26 in yield from the intermediate ester, m.p. 118°-121° C.

Workup

  1. customThe title product was then prepared

Sources & evidence

ORD record
ord-931617218572484999b2533fb8e17b4a
Source dataset
uspto-grants-1996_10
Patent number
US05563278

Reaction notes

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