HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4-Dimethyl-3-pyridinecarboxylic acid → 4-Isopropyl-6-methoxy-4,5,6,7-tetrahydro-2-saccharinylmethyl 2,4-dimethylpyridine-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4-Dimethyl-3-pyridinecarboxylic acid | HCID 1512561 | — |
| Reactant | 2-Chloromethyl-4-isopropyl-6-methoxy-4,5,6,7-tetrahydrosaccharin | HCID 70044009 | — |
| Product | 4-Isopropyl-6-methoxy-4,5,6,7-tetrahydro-2-saccharinylmethyl 2,4-dimethylpyridine-3-carboxylate | HCID 70048945 | — |
Reaction Steps
It is contemplated that following the procedure of Example 17, 2-chloromethyl-4-isopropyl-6-methoxy-4,5,6,7-tetrahydrosaccharin of preparation 23BJ can be coupled with 2,4-dimethyl-3-pyridinecarboxylic acid to provide 4-isopropyl-6-methoxy-4,5,6,7-tetrahydro-2-saccharinylmethyl 2,4-dimethylpyridine-3-carboxylate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05563163 |
| Source dataset | uspto-grants-1996_10 |
| ORD ID | ord-94493dcfc4d44f5f9ead1e976ee13be1 |
| Source note | uspto-grants-1996_10 |