Hydrazine → HCID 23374876, compound

HRID 864889Notes

Reaction equation

HRID 864889 reaction equation
C1(=O)[N:5]([O:6][CH:7]([CH:20]([C:24]([CH3:27])([CH3:26])[CH3:25])[C:21]([OH:23])=[O:22])[CH2:8][N:9]2C(=O)C3=CC=CC=C3C2=O)C(=O)C2=CC=CC=C12.NN>CO>[NH2:5][O:6][CH:7]([CH:20]([C:24]([CH3:27])([CH3:26])[CH3:25])[C:21]([OH:23])=[O:22])[CH2:8][NH2:9]

Participants

4

Reactant 2

HCID 9321HydrazineHCID 57244168HCID 57244168, compound

Product 1

HCID 23374876HCID 23374876, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A mixture of 1,3-diphthalimido-2-(t-butylcarboxymethyl)oxapropane(0.50 g, 1.08 mmol) and 55% hydrazine (0.23 mL, 4.6 mmol) in 2 mL of methanol is refluxed for 4 hrs. After cooling the reaction solution to room temperature, the solids are filtered and the filtrate is evaporated under reduced pressure to yield 1,3-diamino-2-(t-butylcarboxymethyl)oxapropane.

Workup

  1. temperatureis refluxed for 4 hrs
  2. filtrationthe solids are filtered
  3. customthe filtrate is evaporated under reduced pressure

Sources & evidence

ORD record
ord-cc04073983104b0fbc22b1d1a6d4c3b1
Source dataset
uspto-grants-1996_10
Patent number
US05565184

Reaction notes

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