反应详情

A mixture of ethyl 4-amino-1-piperidinecarboxylate (3.53 g, 20.5 mmol) and 4-ethoxy-3-nitropyridine (3.65 g, 21/7 mmol) in CH3CN (25 mL) was heated at reflux for 40 hours. The reaction mixture was cooled to ambient temperature and concentrated in vacuo to give an orange syrup which was used without further purification.

1. temperaturewas heated
2. temperatureat reflux for 40 hours
3. concentrationconcentrated in vacuo
4. customto give an orange syrup which
5. customwas used without further purification