HCID 54426295, compound → Methyl 3-(5-methyl-2-furanyl)propionate

HRID 865692Notes

Reaction equation

HRID 865692 reaction equation
[CH3:1][C:2]1[O:6][C:5]([CH:7]=[CH:8][C:9]([O:11][CH2:12]C)=[O:10])=[CH:4][CH:3]=1>CO.[Pd]>[CH3:1][C:2]1[O:6][C:5]([CH2:7][CH2:8][C:9]([O:11][CH3:12])=[O:10])=[CH:4][CH:3]=1

Participants

4

Reactant 1

HCID 54426295HCID 54426295, compound

Product 1

HCID 14906307Methyl 3-(5-methyl-2-furanyl)propionateYield 107.1%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

A mixture of ethyl β-(5-methyl-2-furanyl)acrylate (8 g) in methanol (200 mL) and 1.5 g of 5% palladium on carbon was placed on a Paar hydrogenator and hydrogenated with H2. Palladium on carbon was filtered off by passing the reaction mixture through Super-Cel™ (filter agent) and the residue was washed with ethanol. The filtrate was concentrated in vacuo to yield 8 g of methyl 3-(5-methyl-2-furanyl)propionate.

Workup

  1. filtrationPalladium on carbon was filtered off
  2. filtrationthrough Super-Cel™ (filter agent)
  3. washthe residue was washed with ethanol
  4. concentrationThe filtrate was concentrated in vacuo

Sources & evidence

ORD record
ord-02ed42084638468ba10b2742216dcfa8
Source dataset
uspto-grants-1996_10
Patent number
US05567717

Reaction notes

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