Dichloromethane → 2,3-Di-(2-n-butoxy ethoxy)propanol

HRID 865785Notes

Reaction equation

HRID 865785 reaction equation
C([O:5][CH2:6][CH:7]([O:17][CH2:18][CH2:19][O:20][CH2:21][CH2:22][CH2:23][CH3:24])[CH2:8][O:9][CH2:10][CH2:11][O:12][CH2:13][CH2:14][CH2:15][CH3:16])(C)(C)C.ClCCl.C(=O)([O-])[O-].[K+].[K+]>C(OCC)C>[CH2:21]([O:20][CH2:19][CH2:18][O:17][CH:7]([CH2:8][O:9][CH2:10][CH2:11][O:12][CH2:13][CH2:14][CH2:15][CH3:16])[CH2:6][OH:5])[CH2:22][CH2:23][CH3:24]

Participants

5

Reactant 3

HCID 6344DichloromethaneHCID 11430Potassium CarbonateHCID 233746721-Tert-butyloxy-2,3-di(2-n-butoxy ethoxy)propane

Product 1

HCID 233746732,3-Di-(2-n-butoxy ethoxy)propanol

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

Compound 31 was prepared as described for 29. The reagents used were as follows, compound 25 (38.0 g, 0.109 mol.), tetrafluoroboric acid-diethyl ether complex (22 ml of a 54% solution in diethyl ether) dichloromethane (100 ml) and excess potassium carbonate. The final yield was a colorless liquid (17.3 g, 59%), (bpt. 95°-120° C., 0.04 torr): 1H-NMR (CDCl3), d, (ppm). Mass spectroscopy, m/e 293 MH+.

Workup

  1. customThe final yield

Sources & evidence

ORD record
ord-77df829410b248058dbc5f6fbd8ebf6f
Source dataset
uspto-grants-1996_10
Patent number
US05567783

Reaction notes

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