Ethanol → HCID 3089143, compound

HRID 865812Notes

Reaction equation

HRID 865812 reaction equation
[CH2:1]([OH:3])[CH3:2].[NH2:4][C:5]1[CH:10]=[C:9]([N+:11]([O-:13])=[O:12])[CH:8]=[CH:7][C:6]=1O>CN(C)C=O>[N+:11]([C:9]1[CH:10]=[CH:5][C:2]([C:1]2[O:3][C:6]3[CH:7]=[CH:8][C:9]([N+:11]([O-:13])=[O:12])=[CH:10][C:5]=3[N:4]=2)=[CH:7][CH:8]=1)([O-:13])=[O:12]

Participants

4

Reactant 2

HCID 702EthanolHCID 36133892-Amino-4-Nitrophenol

Product 1

HCID 3089143HCID 3089143, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

About 60 grams (0.3 mole) of the 4-nitro-phenylchloroxime is mixed with 340 milliliters of ethanol, 60 grams (0.39 moles) of 2-amino-4-nitrophenol and 60 milliliters of dimethylformamide. The mixture is heated to reflux for about 6.5 hours, filtered, washed with methanol and air dried. Approximately 55 grams of 2-(p-nitrophenyl)-5-nitrobenzoxazole are obtained.

Workup

  1. temperatureThe mixture is heated
  2. temperatureto reflux for about 6.5 hours
  3. filtrationfiltered
  4. washwashed with methanol and air
  5. customdried

Sources & evidence

ORD record
ord-2f6e123565e744e3ba17ca366cfc29ef
Source dataset
uspto-grants-1996_10
Patent number
US05567843

Reaction notes

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