Triethyl phosphite → Diethyl (Methoxymethyl)phosphonate

Participants

Reaction Steps

To a sample of 17.90 mL (0.104 mol) of triethylphosphite at -78° C. under argon was added, dropwise 8.50 mL (0.104 mol) of bromomethyl methyl ether. The mixture slowly warmed to RT and stirred for 24 h, when it was fractionally distilled 100° C., 5 mm) to provide 16.22 g (98%) of title compound as a pale yellow oil.

Provenance & Evidence