3-(1-Propenyl)phenol → 3-Propylphenol

HRID 865879Notes

Reaction equation

HRID 865879 reaction equation
[CH:1]([C:4]1[CH:5]=[C:6]([OH:10])[CH:7]=[CH:8][CH:9]=1)=[CH:2][CH3:3].[H][H]>[Pd].C1COCC1>[CH2:1]([C:4]1[CH:5]=[C:6]([OH:10])[CH:7]=[CH:8][CH:9]=1)[CH2:2][CH3:3]

Participants

5

Reactant 2

HCID 539593403-(1-Propenyl)phenolHCID 178418361HCID 178418361, compound

Product 1

HCID 693023-PropylphenolYield 100%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8028TetrahydrofuranSolvent

Procedure

To a mixture of Part B (1) compound (3 g, 22.4 mmol) and 10% palladium on carbon (150 mg) in THF (25 mL) was connected a hydrogen balloon. Hydrogenation was maintained at RT overnight. The mixture of reaction was filtered through Celite. The resulting clear solution was evaporated to give the title compound (2.97 g, 100%) as a yellowish oil.

Workup

  1. additionThe mixture of reaction
  2. filtrationwas filtered through Celite
  3. customThe resulting clear solution was evaporated

Sources & evidence

ORD record
ord-09957463178a40dfa468e286b9e85195
Source dataset
uspto-grants-1996_10
Patent number
US05567841

Reaction notes

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