HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 865938Generated: October 25, 2026
Boron tribromide → 2,3-Dihydro-1,4-benzodioxin-5-ol
https://huagongshe.com/reaction/865938
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Boron tribromide | HCID 25134 | — |
| Reactant | 2,3-Dihydro-5-methoxy-1,4-benzodioxin | HCID 74371 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2,3-Dihydro-1,4-benzodioxin-5-ol | HCID 82520 | — |
Reaction Steps
At 0° C., boron tribromide (5.6 cm3) is added slowly to a solution of 5-methoxy-1,4-benzodioxane (5 g, 30.1 mmol) in 25 cm3 of CH2Cl2. The mixture is stirred at 0° C. for 15 min, the solution is then hydrolysed with 10 cm3 of water and the product is extracted with CH2Cl2. Purification on a silica column (eluent: 100% CH2Cl2) enables 4.49 g of a colorless oil to be obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05569669 |
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| Source dataset | uspto-grants-1996_10 |
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| ORD ID | ord-ce06de15ee3d4369a4a6f27e4b83b51b |
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| Source note | uspto-grants-1996_10 |
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