反应详情

A reaction mixture of 3.1 g (19.74 mmol) of 2-(1,3-dioxolan-2-yl)thiazole and 3.38 g (19.74 mmol) of benzyl bromide was heated on a steam-bath with stirring for 6 h. The mixture was cooled to room temperature, triturated with ethyl acetate and decanted to afford 5.5 g (84.9%) of 3-benzyl-2-(1,3-dioxolan-2-yl)thiazolium bromide (Formula VI: A=2-thiazolyl;Y=1,3-dioxolan-2-yl; R1 =R6 =H;Z- =Br-).

1. temperaturewas heated on a steam-bath
2. customtriturated with ethyl acetate
3. customdecanted