Benzyl Bromide → HCID 178481934, compound

HRID 865948Notes

Reaction equation

HRID 865948 reaction equation
[O:1]1[CH2:5][CH2:4][O:3][CH:2]1[C:6]1[N:10]([CH3:11])[N:9]=[CH:8][N:7]=1.[CH2:12]([Br:19])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[Br-:19].[CH2:12]([N:7]1[C:6]([CH:2]2[O:3][CH2:4][CH2:5][O:1]2)=[N+:10]([CH3:11])[N:9]=[CH:8]1)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 7498Benzyl BromideHCID 19974094HCID 19974094, compound

Product 1

HCID 178481934HCID 178481934, compoundYield 64.1%

Procedure

A reaction mixture of 2.3 g (14.83 mmol) of 5-(1,3-dioxolan-2-yl)-1-methyl-1,2,4-triazole and 2.53 g (14.83 mmol) of benzyl bromide was heated on a steam-bath with stirring for 48 h. The mixture was cooled to room temperature, triturated with ethyl acetate and decanted to afford 3.1 g (64.1%) of 4-benzyl-5-(1,3-dioxolan-2-yl)-1-methyl-1,2,4-triazolium bromide (Formula VI: A=1-methyl-1,2,4-triazolo;Y=5-(1,3-dioxolan-2-yl);R1 =R6 =H; Z- =Br-).

Workup

  1. temperaturewas heated on a steam-bath
  2. customtriturated with ethyl acetate
  3. customdecanted

Sources & evidence

ORD record
ord-ec254d8b182b4497a1d370f2498d1f19
Source dataset
uspto-grants-1996_10
Patent number
US05569655

Reaction notes

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