Azepane → HCID 12449101, compound

HRID 866332Notes

Reaction equation

[NH:1]1[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[N:8]#[C:9]Br.[OH-].[Na+]>>[N:1]1([C:9]#[N:8])[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

Reactant 3

HCID 8119Azepane

HCID 10476Cyanogen Bromide

HCID 14798Sodium Hydroxide

Product 1

HCID 12449101HCID 12449101, compound

Procedure

In the manner given in Example 1, hexahydroazepine is treated with cyanogen bromide and aqueous sodium hydroxide to give 1-hexahydroazepinecarbonitrile.

Sources & evidence

ORD record: ord-1e0b55a33d5546f7b7e3e089a70b994d
Source dataset: uspto-grants-1978_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04098791

Reaction notes

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