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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 866335Generated: October 30, 2026

Cyanogen Bromide → 4-METHYL-PIPERAZINE-1-CARBONITRILE

https://huagongshe.com/reaction/866335

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyanogen BromideHCID 10476—
ReactantSodium HydroxideHCID 14798—
Reactant1-MethylpiperazineHCID 53167—
Product4-METHYL-PIPERAZINE-1-CARBONITRILEHCID 10419183—

Reaction Steps

In the manner given in Example 1, N-methylpiperazine is treated with cyanogen bromide and aqueous sodium hydroxide to give 4-methyl-1-piperazinecarbonitrile.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04098791
Source datasetuspto-grants-1978_07
ORD IDord-60421e53c55e4d9583bbf1b39cf49d92
Source noteuspto-grants-1978_07