Formaldehyde → HCID 54405233, compound

Participants

Reaction Steps

103 g. of 1-amino ethane-1,1-diphosphonic acid are suspended in 100 g. of a 30% formaldehyde solution. 85 cc. of phosphorus trichloride are added thereto drop by drop while stirring. After the addition is completed, the mixture is heated to boiling until a homogeneous mixture is formed. The water is removed by evaporation in a vacuum. The resulting phosphonic acid mixture is precipitated by the addition of acetone. N-phosphono methylene-1-amino ethane-1,1-diphosphonic acid is obtained in this manner.

Provenance & Evidence