Water → Ethanediamide, N1,N2-bis(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-

HRID 866523ノート

反応式

HRID 866523 の反応式
[C:1]1(=[O:11])O[C:4](=[O:5])[C:3]2=[CH:7][CH:8]=[CH:9][CH:10]=[C:2]12.[C:12]([NH:18][NH2:19])(=[O:17])[C:13]([NH:15][NH2:16])=[O:14].[OH2:20]>C1(C)C(C)=CC=CC=1>[C:4]1(=[O:5])[N:16]([NH:15][C:13]([C:12]([NH:18][N:19]2[C:1](=[O:11])[C:2]3=[CH:10][CH:9]=[CH:8][CH:7]=[C:3]3[C:4]2=[O:5])=[O:17])=[O:14])[C:1](=[O:20])[C:2]2=[CH:10][CH:9]=[CH:8][CH:7]=[C:3]12

参加物

5

反応物 3

HCID 962WaterHCID 6811Phthalic AnhydrideHCID 13826Oxalic acid, dihydrazide

生成物 1

HCID 113193Ethanediamide, N1,N2-bis(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-収率 94%

試薬・触媒・溶媒 1

HCID 7237O-Xylene溶媒

実験手順

Two moles of phthalic anhydride (296g) and one mole of oxalic dihydrazide (118 g) in xylene (2.5 l) were heated at reflux until two moles of water were removed (about 24 hours). The product was filtered and dried at 50° C. N,N'-bis(phthalimido)-oxamide was obtained in 94-6 percent yield. The compound was a white solid melting at 295° C (dec.) and having the following elemental analysis by weight percent:

後処理

  1. customwere removed (about 24 hours)
  2. filtrationThe product was filtered
  3. customdried at 50° C

出典と根拠

ORDレコード
ord-b37e282ca629479f922fa055cd857357
出典データセット
uspto-grants-1978_07
特許番号
US04100132

反応ノート

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