Hydrochloric Acid → HCID 22743615, compound

HRID 866764Notes

Reaction equation

HRID 866764 reaction equation
[CH2:1]([C:4]1([C:13]([C:16]([O:18]CC)=[O:17])([CH3:15])[CH3:14])[C:9](=[O:10])[NH:8][C:7](=[O:11])[NH:6][C:5]1=[O:12])[CH:2]=[CH2:3].Cl>>[CH2:1]([C:4]1([C:13]([C:16]([OH:18])=[O:17])([CH3:14])[CH3:15])[C:9](=[O:10])[NH:8][C:7](=[O:11])[NH:6][C:5]1=[O:12])[CH:2]=[CH2:3]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 20532011HCID 20532011, compound

Product 1

HCID 22743615HCID 22743615, compound

Procedure

A mixture of 50 g. of 5-allyl-5-(1-ethoxycarbonyl-isopropyl)barbituric acid and 400 ml. of 1N hydrochloric acid was heated under reflux for 4 hours. The solution was allowed to stand at room temperature overnight and the precipitate was collected to yield 42.5 g. (94%) of the acid, m.p. 202°-203°.

Workup

  1. additionA mixture of 50 g
  2. temperatureunder reflux for 4 hours
  3. customthe precipitate was collected
  4. customto yield 42.5 g

Sources & evidence

ORD record
ord-7a58646de2a248d9a21111f550373dc7
Source dataset
uspto-grants-1978_07
Patent number
US04101549

Reaction notes

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