Ammonia → HCID 18925560, compound

HRID 866862Notes

Reaction equation

HRID 866862 reaction equation
[CH3:1][C:2]1[CH:17]=[CH:16][C:5]([CH:6]([N:13]=[C:14]=[S:15])[C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[CH:4][CH:3]=1.[NH3:18]>CCOCC>[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([CH:6]([NH:13][C:14]([NH2:18])=[S:15])[C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[CH:16][CH:17]=1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 21312345HCID 21312345, compound

Product 1

HCID 18925560HCID 18925560, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A solution of 22 g (0.092 mole) of 4-methylbenzhydrylisothiocyanate in 250 ml of dry ether at 0° is treated with anhydrous NH3 for 3 hours while stirring. The mixture is stirred an additional 1.5 hours at 0° to 10° C during which time the crude product precipitates as a white solid. Filtration and washing with Et2O affords the product; mp 167°-8° C.

Workup

  1. customprecipitates as a white solid
  2. filtrationFiltration
  3. washwashing with Et2O
  4. customaffords the product

Sources & evidence

ORD record
ord-b38774d4bd574178b8c3d56ed63ba0ad
Source dataset
uspto-grants-1978_07
Patent number
US04101659

Reaction notes

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