Hydrazine hydrate (1:1) → HCID 178427940, compound

HRID 866939Notes

Reaction equation

HRID 866939 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([NH:8][C:9](=[NH:12])SC)[CH:5]=[C:4]([Cl:13])[C:3]=1[CH3:14].[NH2:15][NH2:16].O>C(O)C>[Cl:1][C:2]1[CH:7]=[C:6]([NH:8][C:9]([NH2:12])=[N:15][NH2:16])[CH:5]=[C:4]([Cl:13])[C:3]=1[CH3:14]

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 178504006HCID 178504006, compound

Product 1

HCID 178427940HCID 178427940, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To 7.18 g of 1-(2,6-dichloro-4-tolyl)-2-methylisothiourea.HJ (C), suspended in 26 ml of ethanol, 1.3 ml of hydrazine.hydrate is added after which the mixture is refluxed for 20 hours. The precipitate formed is filtered off and the filtrate evaporated to dryness. Yield: 6.35 g. Melting point HJ salt: 203°-205° C; melting point HCl salt: 149°-150° C.

Workup

  1. temperatureis refluxed for 20 hours
  2. customThe precipitate formed
  3. filtrationis filtered off
  4. customthe filtrate evaporated to dryness
  5. custom203°-205° C
  6. custom149°-150° C.

Sources & evidence

ORD record
ord-2f6520e31cb04f728e46a2695e9c7050
Source dataset
uspto-grants-1978_07
Patent number
US04101675

Reaction notes

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