Piperidine → HCID 20319076, compound

HRID 866967Notes

Reaction equation

HRID 866967 reaction equation
[NH2:1][C:2]1[CH:9]=[CH:8][C:7]([O:10][CH3:11])=[CH:6][C:3]=1[CH2:4]O.S(Cl)(Cl)=O.[NH:16]1[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1>C(Cl)Cl>[NH2:1][C:2]1[CH:9]=[CH:8][C:7]([O:10][CH3:11])=[CH:6][C:3]=1[CH2:4][N:16]1[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1

Participants

5

Reactant 3

HCID 8082PiperidineHCID 24386Thionyl ChlorideHCID 13756678(2-Amino-5-methoxyphenyl)methanol

Product 1

HCID 20319076HCID 20319076, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

N-(2-Amino-5-methoxy-benzyl)-piperidine was prepared from 2-amino-5-methoxy-benzyl alcohol, thionyl chloride and piperidine analogous to Example 1. Proof of structure by IR- and UV-spectra. IR-spectrum (methylenechloride):

Sources & evidence

ORD record
ord-975fa46c2a0f4c4e9d44cb9c84dd00d9
Source dataset
uspto-grants-1978_07
Patent number
US04101671

Reaction notes

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