Sodium Iodide → HCID 54574466, compound

HRID 867063Notes

Reaction equation

HRID 867063 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N:16]=[C:17]([O:20][CH2:21][CH3:22])[CH2:18]Br)=[C:6]([CH:15]=1)[C:7]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=[O:8].[I-:23].[Na+]>CC(C)=O>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N:16]=[C:17]([O:20][CH2:21][CH3:22])[CH2:18][I:23])=[C:6]([CH:15]=1)[C:7]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=[O:8]

Participants

4

Reactant 2

HCID 5238Sodium IodideHCID 20317273HCID 20317273, compound

Product 1

HCID 54574466HCID 54574466, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent2×

Procedure

To a solution of 3.8 parts of 5-chloro-2-(2-bromo-1-ethoxyethylideneamino)benzophenone in 30 parts by volume of acetone is added with stirring a solution of 1.5 parts of sodium iodide in 12 parts by volume of acetone. After about one hour, the resulting precipitate is removed by filtration. The filtrate is concentrated under reduced pressure. The concentrate is treated with petroleum ether to give 5-chloro-2-(1-ethoxy-2-iodoethylideneamino)benzophenone as crystals. The crystals are recrystallized from n-hexane to give pale brown pillars melting at 67°-68° C.

Workup

  1. customthe resulting precipitate is removed by filtration
  2. concentrationThe filtrate is concentrated under reduced pressure
  3. additionThe concentrate is treated with petroleum ether

Sources & evidence

ORD record
ord-0839591a657d4ad58644b4ed3c61d1fb
Source dataset
uspto-grants-1978_07
Patent number
US04102881

Reaction notes

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