Methyl iodide → HCID 10616100, compound

HRID 867196Notes

Reaction equation

HRID 867196 reaction equation
[O-][CH2:2]C.[Na+].[NH:5]1[C:9]([C:10]2[CH:11]=[CH:12][C:13]3[C:14](=[O:26])[C:15]4[C:20]([S:21](=[O:25])(=[O:24])[C:22]=3[CH:23]=2)=[CH:19][CH:18]=[CH:17][CH:16]=4)=[N:8][N:7]=[N:6]1.CI>C(O)C>[CH3:2][N:7]1[N:6]=[N:5][C:9]([C:10]2[CH:11]=[CH:12][C:13]3[C:14](=[O:26])[C:15]4[C:20]([S:21](=[O:24])(=[O:25])[C:22]=3[CH:23]=2)=[CH:19][CH:18]=[CH:17][CH:16]=4)=[N:8]1

Participants

5

Reactant 3

HCID 6328Methyl iodideHCID 2723922Sodium ethoxideHCID 178515054HCID 178515054, compound

Product 1

HCID 10616100HCID 10616100, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a solution of sodium ethoxide in ethanol (20 ml) (prepared from 0.46 g sodium) was added 3-(5-tetrazolyl) thioxanthone-10,10-dioxide (6.24g). Methyl iodide (2.84 g) was added and the mixture boiled under reflux for 2 hrs. During the reflux period a yellow product was deposited. On cooling it was filtered off, washed with water and recrystallised twice from acetic acid to give 3-(2-methyl-5-tetrazolyl)thioxanthone-10,10-dioxide as yellow needles, m.p. 204°-205° C.

Workup

  1. temperatureunder reflux for 2 hrs
  2. temperatureOn cooling it
  3. filtrationwas filtered off
  4. washwashed with water
  5. customrecrystallised twice from acetic acid

Sources & evidence

ORD record
ord-62b3e132b37e4e1387e1affdba498afd
Source dataset
uspto-grants-1978_07
Patent number
US04103015

Reaction notes

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