Benzoylacetone → HCID 67906974, compound

HRID 867352Notes

Reaction equation

HRID 867352 reaction equation
[C:1]([CH2:9][C:10](=O)[CH3:11])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[N:13]1([CH2:19][CH2:20][NH2:21])[CH2:18][CH2:17][O:16][CH2:15][CH2:14]1>C1(C)C=CC=CC=1>[N:13]1([CH2:19][CH2:20][NH:21][C:10]([CH3:11])=[CH:9][C:1](=[O:8])[C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)[CH2:18][CH2:17][O:16][CH2:15][CH2:14]1

Participants

4

Reactant 2

HCID 7166BenzoylacetoneHCID 4082852-Morpholinoethylamine

Product 1

HCID 67906974HCID 67906974, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

A solution of 28.7 g. (0.177 mole) of benzoylacetone and 23.2 ml. (0.177 mole) of 2-(4-morpholinyl)ethylamine in 600 ml. of toluene was heated under reflux for ten and a half hours under a Dean-Stark trap and the solution then cooled and taken to dryness to give N-[2-(4-morpholinyl)ethyl]-N-(1-methyl-3-oxo-3-phenylpropenyl)amine as a yellow solid.

Workup

  1. temperatureunder reflux for ten and a half hours under a Dean-Stark trap
  2. temperaturethe solution then cooled

Sources & evidence

ORD record
ord-86f7c5308fda4e5c8a236718c50fec7b
Source dataset
uspto-grants-1988_10
Patent number
USRE032761

Reaction notes

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